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Publication number WO A1 Publication type Application Application number PCT/US2016/064037 Publication date Jun 8, 2017 Filing date Nov 29, 2016 Priority date Nov 30, 2015 Publication number PCT/2016/64037, PCT/US/16/064037, PCT/US/16/64037, PCT/US/2016/064037, PCT/US/2016/64037, PCT/US16/064037, PCT/US16/64037, PCT/US16064037, PCT/US1664037, PCT/US2016/064037, PCT/US2016/64037, PCT/US, PCT/US201664037, WO 2017/095826 A1, WO A1, WO A1, WO-A1-, WO2017/095826A1, WO A1, WOA1 Inventors,, Applicant Export Citation,, (3), (2), (6), (1) External Links. The present disclosure provides a pharmaceutical composition that inhibits the proliferation of a cancer cell, comprising a first compound selected from indole-3- carbinol (I3C), 1-benzyl I3C, or a pharmaceutically acceptable salt or ester thereof, and a second compound that binds to and inhibits: i) an oncogenic RAF polypeptide at a site that is distinct from the site at which the first compound binds; ii) a polypeptide of the RAF signaling pathway; iii) a polypeptide of the Wnt-β-catenin signaling pathway; iv) or a polypeptide of the PI3K/AKT/mTOR signaling pathway. The present disclosure also provides a method of treating cancer in a subject. COMBINATION THERAPY FOR TREATMENT OF MELANOMA CROSS-REFERENCE [0001] This application claims the benefit of U.S. Provisional Patent Application No. 62/261,020, filed November 30, 2015, which application is incorporated herein by reference in its entirety. Bank Of England Font Free 03 Adolescence Lyrics Clean By Natalie. more.

Use of pei for the improvement of endosomal release and expression of transfected nucleic acids, complexed with cationic or polycationic compounds. The present invention relates to an immunostimulatory composition comprising a) an adjuvant component, comprising or consisting of at least one (m)RNA, complexed with. Eton Et866 Drivers.